Title

Effects of anesthesia and other perioperative factors on immune function: a narrative review.

Authors

Yining Chen; Junwei Kang; Yulang Wang; Xiongxiong Pan

Abstract

This study investigates the impact of perioperative factors on patients' immune functions including physiological condition, surgical strategy, anesthesia methodology, intraoperative usage of anesthetics, blood transfusion, intraoperative body temperature, and inspired oxygen concentration. Results demonstrate that the individual perioperative factors have varying degree of impact, while their combined effect may cause changes in patients' immune function. The study outcomes suggest that patient's immune function must be assessed prior to the surgery based on individual characteristics. The surgical and anesthetic methods are accordingly selected. During the surgery, prudent usage and monitoring of factors like anesthesia techniques, anesthetics, inhaled oxygen concentration, blood transfusion, and patient's body temperature are vital for minimizing the immune system disruptions. These findings practically guide regarding the optimization of perioperative care strategies and mitigation of immunosuppression risks.

Subjects

BLOOD transfusion; PERIOPERATIVE care; BODY temperature; ANESTHETICS; ANESTHESIA

Publication

Signa Vitae, 2024, Vol 20, Issue 9, p1

ISSN

1334-5605

Publication type

Academic Journal

DOI

10.22514/sv.2024.105