Title

Wound healing promoting activity of Earthworm, Eutyphoeus gammiei (Beddard): in vitro studies on human skin keratinocyte cell line (HaCat).

Authors

Susmita, Saha; Deepjyoti, Bhattacharjee; Anwesha, Saha; Gahin, De; Partha, Saha; Kumar, Sil Samir

Abstract

Earthworm, Eutyphoeus gammiei, homogenate (EGH) was screened for wound healing activity on human keratinocyte cell line, HaCat, by cell proliferation and migration assays. The maximum proliferation and migration of keratinocyte cells were observed at the dose of 25µg/ml. As cell proliferation and migration are key factors for wound healing, the study clearly suggests the potential role of earthworm species Eutyphoeus gammiei on wound healing.

Subjects

WOUND healing; EARTHWORMS; KERATINOCYTES; CELL lines; CELL proliferation

Publication

Journal of Drug Delivery & Therapeutics, 2018, Vol 8, Issue 6, p155

ISSN

2250-1177

Publication type

Academic Journal

DOI

10.22270/jddt.v8i6.2036