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- Title
Effect of Human Testicular Cells Conditioned Medium on <i>In Vitro</i> Maturation and Morphology of Mouse Oocytes.
- Authors
Adib, Maryam; Seifati, Seyed Morteza; Dehghani Ashkezari, Mahmood; Akyash, Fatemeh; Khoradmehr, Arezoo; Aflatoonian, Behrouz
- Abstract
Testicular cell conditioned medium (TCCM) has been shown to induce female germ cell development In Vitro from embryonic stem cells (ESCs). Testicular cells (TCs) secrete a variety of growth factors such as growth differentiation factor-9 (GDF-9), bone morphogenetic protein 4 (BMP-4), stem cell factor (SCF), leukemia inhibitory factor (LIF), and other, that could improve oocyte maturation. Here we have investigated the effect of human TCCM (hTCCM) on in vitro maturation (IVM) and morphology of mouse oocytes.
- Publication
International journal of fertility & sterility, 2020, Vol 14, Issue 3, p175
- ISSN
2008-076X
- Publication type
Journal Article
- DOI
10.22074/ijfs.2020.6097