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- Title
Opioid-paracetamol prescription patterns and liver dysfunction: a retrospective cohort study in a population served by a US health benefits organization.
- Authors
Mort, Jane R; Shiyanbola, Olayinka O; Ndehi, Lilian N; Xu, Yihua; Stacy, Jane N
- Abstract
Paracetamol (acetaminophen) is the most common cause of acute liver failure (ALF). ALF attributed to paracetamol is most often associated with the following features: an unintentional overdose, a single product, an opioid-paracetamol combination, duration of <7 days, and a median dose of 7.5 g/day. Currently, the recommended maximum daily dose of paracetamol is 4 g.
- Publication
Drug safety, 2011, Vol 34, Issue 11, p1079
- ISSN
1179-1942
- Publication type
Journal Article
- DOI
10.2165/11593100-000000000-00000