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- Title
Pharmacokinetics of oxybutynin chloride topical gel: effects of application site, baths, sunscreen and person-to-person transference.
- Authors
Dmochowski, Roger R; Newman, Diane K; Sand, Peter K; Rudy, Delbert C; Caramelli, Kim E; Thomas, Heather; Hoel, Gary
- Abstract
Oxybutynin chloride topical gel (OTG; Gelnique®) is an approved formulation for the transdermal administration of oxybutynin, an established antimuscarinic therapy for overactive bladder (OAB). Transdermal administration of oxybutynin minimizes plasma concentrations of the active metabolite N-desethyloxybutynin (N-DEO), which can have anticholinergic adverse effects.
- Publication
Clinical drug investigation, 2011, Vol 31, Issue 8, p559
- ISSN
1179-1918
- Publication type
Journal Article
- DOI
10.2165/11588990-000000000-00000