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- Title
Isotretinoin use and compliance with the Dutch Pregnancy Prevention Programme: a retrospective cohort study in females of reproductive age using pharmacy dispensing data.
- Authors
Teichert, Martina; Visser, Loes E; Dufour, Mark; Rodenburg, Eline; Straus, Sabine M J M; De Smet, Peter A G M; Stricker, Bruno H Ch
- Abstract
Isotretinoin is very effective in the treatment of severe acne. However, because of the teratogenic properties of this agent an isotretinoin Pregnancy Prevention Programme (PPP) was implemented in the Netherlands to guarantee that treatment is contraindicated in women of reproductive age unless at least one effective method of contraception is used. Furthermore, the PPP stipulates that isotretinoin treatment should be managed by physicians or specialists experienced in treatment with this drug and that only monthly prescriptions are issued.
- Publication
Drug safety, 2010, Vol 33, Issue 4, p315
- ISSN
1179-1942
- Publication type
Journal Article
- DOI
10.2165/11319190-000000000-00000