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- Title
Tramadol has a better potency ratio relative to morphine in neuropathic than in nociceptive pain models.
- Authors
Christoph, Thomas; Kögel, Babette; Strassburger, Wolfgang; Schug, Stephan A
- Abstract
Treatment of neuropathic pain remains a challenge and the role of various analgesics in this setting is still debated. The effects of tramadol, an atypically acting analgesic with a combined opioid and monoaminergic mechanism of action, and morphine, a prototypical opioid, were tested in rat models of neuropathic and nociceptive pain.
- Publication
Drugs in R&D, 2007, Vol 8, Issue 1, p51
- ISSN
1174-5886
- Publication type
Journal Article
- DOI
10.2165/00126839-200708010-00005