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- Title
Effects of concurrent therapy with policosanol and omega-3 fatty acids on lipid profile and platelet aggregation in rabbits.
- Authors
Gámez, R; Máz, R; Arruzazabala, M L; Mendoza, S; Castaño, G
- Abstract
Policosanol is a mixture of high-molecular-weight aliphatic primary alcohols isolated from sugarcane wax with cholesterol-lowering and antiplatelet effects. Omega-3 fatty acids (FA) from fish oil can protect against coronary disease. An antiarrhythmic mechanism is emerging as the most convincing explanation for omega-3 FA cardiovascular protection, but triglyceride (TG)-lowering effects and inhibition of platelet function could play a role. In view of the effects of policosanol and omega-3 FA on lipid profile and platelet function, potential benefits of combined therapy were expected.
- Publication
Drugs in R&D, 2005, Vol 6, Issue 1, p11
- ISSN
1174-5886
- Publication type
Journal Article
- DOI
10.2165/00126839-200506010-00002