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- Title
Comparison of the effects of policosanol and atorvastatin on lipid profile and platelet aggregation in patients with dyslipidaemia and type 2 diabetes mellitus.
- Authors
Castaño, Gladys; Fernández, Lilia; Mas, Rosa; Illnait, José; Mesa, Meylin; Fernández, J C
- Abstract
Diabetes mellitus and hypercholesterolaemia increase the risk for coronary heart disease, with type 2 diabetes mellitus being the most prevalent form of diabetes, frequently accompanied by dyslipidaemia. The main goal of dyslipidaemia control in nondiabetic and diabetic patients is to lower elevated low-density lipoprotein-cholesterol (LDL-C) levels. Policosanol is a cholesterol-lowering drug, purified from sugarcane wax, with a therapeutic range of 5-20 mg/day, which significantly reduces LDL-C levels. Atorvastatin is an HMG-CoA reductase inhibitor that, across its dose range (10-80 mg/day), has shown significantly greater lipid-lowering effects than all previously marketed statins.
- Publication
Clinical drug investigation, 2003, Vol 23, Issue 10, p639
- ISSN
1173-2563
- Publication type
Journal Article
- DOI
10.2165/00044011-200323100-00003