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- Title
Discontinuation of methotrexate therapy in older patients with newly diagnosed rheumatoid arthritis: analysis of administrative health databases in Québec, Canada.
- Authors
Bernatsky, Sasha; Ehrmann Feldman, Debbie
- Abstract
Rheumatoid arthritis (RA) is a potentially devastating form of chronic arthritis. Methotrexate is the cornerstone of drug therapy of the disorder, and may slow or prevent joint damage. Unfortunately, this agent is not without adverse effects. Furthermore, increasing age has been been invoked as a predictor of greater toxicity and drug discontinuation by some, but not all, investigators.
- Publication
Drugs & aging, 2008, Vol 25, Issue 10, p879
- ISSN
1170-229X
- Publication type
Journal Article
- DOI
10.2165/00002512-200825100-00007