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- Title
Statins, neuromuscular degenerative disease and an amyotrophic lateral sclerosis-like syndrome: an analysis of individual case safety reports from vigibase.
- Authors
Edwards, I Ralph; Star, Kristina; Kiuru, Anne
- Abstract
The WHO Foundation Collaborating Centre for International Drug Monitoring (Uppsala Monitoring Centre [UMC]) has received many individual case safety reports (ICSRs) associating HMG-CoA reductase inhibitor drug (statin) use with the occurrence of muscle damage, including rhabdomyolysis, and also peripheral neuropathy. A new signal has now appeared of disproportionally high reporting of upper motor neurone lesions.
- Publication
Drug safety, 2007, Vol 30, Issue 6, p515
- ISSN
0114-5916
- Publication type
Journal Article
- DOI
10.2165/00002018-200730060-00005