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- Title
Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarction.
- Authors
Schlienger, Raymond G; Fischer, Lorenz M; Jick, Hershel; Meier, Christoph R
- Abstract
It has been suggested that increased platelet activation increases the risk of acute myocardial infarction (AMI) in patients with depression. Selective serotonin reuptake inhibitors (SSRIs) may attenuate platelet activation by serotonin depletion in platelets. Observational studies have shown discrepant results of AMI risk associated with the use of SSRIs.
- Publication
Drug safety, 2004, Vol 27, Issue 14, p1157
- ISSN
0114-5916
- Publication type
Journal Article
- DOI
10.2165/00002018-200427140-00006