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- Title
Fabrication and characterization of nuclear localization signal-conjugated glycol chitosan micelles for improving the nuclear delivery of doxorubicin.
- Authors
Yu, Jingmou; Xie, Xin; Zheng, Meirong; Yu, Ling; Zhang, Lei; Zhao, Jianguo; Jiang, Dengzhao; Che, Xiangxin
- Abstract
Supramolecular micelles as drug-delivery vehicles are generally unable to enter the nucleus of nondividing cells. In the work reported here, nuclear localization signal (NLS)-modified polymeric micelles were studied with the aim of improving nuclear drug delivery.
- Publication
International journal of nanomedicine, 2012, Vol 7, p5079
- ISSN
1178-2013
- Publication type
Journal Article
- DOI
10.2147/IJN.S36150