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- Title
Utility of serum procalcitonin values in patients with acute exacerbations of chronic obstructive pulmonary disease: a cautionary note.
- Authors
Falsey, Ann R; Becker, Kenneth L; Swinburne, Andrew J; Nylen, Eric S; Snider, Richard H; Formica, Maria A; Hennessey, Patricia A; Criddle, Mary M; Peterson, Derick R; Walsh, Edward E
- Abstract
Serum procalcitonin levels have been used as a biomarker of invasive bacterial infection and recently have been advocated to guide antibiotic therapy in patients with chronic obstructive pulmonary disease (COPD). However, rigorous studies correlating procalcitonin levels with microbiologic data are lacking. Acute exacerbations of COPD (AECOPD) have been linked to viral and bacterial infection as well as noninfectious causes. Therefore, we evaluated procalcitonin as a predictor of viral versus bacterial infection in patients hospitalized with AECOPD with and without evidence of pneumonia.
- Publication
International journal of chronic obstructive pulmonary disease, 2012, Vol 7, p127
- ISSN
1178-2005
- Publication type
Journal Article
- DOI
10.2147/COPD.S29149