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- Title
Vancomycin-modified implant surface inhibits biofilm formation and supports bone-healing in an infected osteotomy model in sheep: a proof-of-concept study.
- Authors
Stewart, Suzanne; Barr, Stephanie; Engiles, Julie; Hickok, Noreen J; Shapiro, Irving M; Richardson, Dean W; Parvizi, Javad; Schaer, Thomas P
- Abstract
Implant-associated infections contribute to patient morbidity and health care costs. We hypothesized that surface modification of titanium fracture hardware with vancomycin would support bone-healing and prevent bacterial colonization of the implant in a large-animal model.
- Publication
The Journal of bone and joint surgery. American volume, 2012, Vol 94, Issue 15, p1406
- ISSN
1535-1386
- Publication type
Journal Article
- DOI
10.2106/JBJS.K.00886