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- Title
Osteoinductivity of demineralized bone matrix is independent of donor bisphosphonate use.
- Authors
Schwartz, Zvi; Hyzy, Sharon L; Moore, Mark A; Hunter, Shawn A; Ronholdt, Chad J; Sunwoo, MoonHae; Boyan, Barbara D
- Abstract
Demineralized bone matrix is commonly used as a bone graft substitute, either alone or to supplement an osteoconductive material, because of its osteoinductive properties. The aging of the population has led to an increase in the number of prospective donors of demineralized bone matrix who have taken bisphosphonates to prevent osteoclast-mediated bone resorption. The aim of this study was to determine whether oral bisphosphonate usage affects the osteoinductivity of demineralized bone matrix from donors.
- Publication
The Journal of bone and joint surgery. American volume, 2011, Vol 93, Issue 24, p2278
- ISSN
1535-1386
- Publication type
Journal Article
- DOI
10.2106/JBJS.J.01469