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- Title
Reporting of outcomes in orthopaedic randomized trials: does blinding of outcome assessors matter?
- Authors
Poolman, Rudolf W; Struijs, Peter A A; Krips, Rover; Sierevelt, Inger N; Marti, René K; Farrokhyar, Forough; Bhandari, Mohit
- Abstract
Randomization, concealment of treatment allocation, and blinding are all known to limit bias in clinical research. Nonsurgical studies that fail to meet these standards have been reported to inflate the differences between treatment and control groups. While surgical trials can rarely blind surgeons or patients, they can often blind outcome assessors. The aim of this systematic review was threefold: (1) to examine the reporting of outcome measures in orthopaedic trials, (2) to determine the feasibility of blinding in published orthopaedic trials, and (3) to examine the association between the magnitude of treatment differences and the blinding of outcome assessors.
- Publication
The Journal of bone and joint surgery. American volume, 2007, Vol 89, Issue 3, p550
- ISSN
0021-9355
- Publication type
Journal Article
- DOI
10.2106/JBJS.F.00683