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- Title
The effect of collagen nerve conduits filled with collagen-glycosaminoglycan matrix on peripheral motor nerve regeneration in a rat model.
- Authors
Lee, Joo-Yup; Giusti, Guilherme; Friedrich, Patricia F; Archibald, Simon J; Kemnitzer, John E; Patel, Jignesh; Desai, Namrata; Bishop, Allen T; Shin, Alexander Y
- Abstract
Bioabsorbable unfilled synthetic nerve conduits have been used in the reconstruction of small segmental nerve defects with variable results, especially in motor nerves. We hypothesized that providing a synthetic mimic of the Schwann cell basal lamina in the form of a collagen-glycosaminoglycan (GAG) matrix would improve the bridging of the nerve gap and functional motor recovery.
- Publication
The Journal of bone and joint surgery. American volume, 2012, Vol 94, Issue 22, p2084
- ISSN
1535-1386
- Publication type
Journal Article
- DOI
10.2106/JBJS.K.00658