Title

Anti-fatigue Effect of Water Extract from Centella asiatica (L.) Urban on Mice.

Authors

Chunmei MO; Jinye LIN; Yanfang MA; Jiajie ZHOU; Ling LLANG; Nian LIN; Suoyi HUANG; Gang XIAO

Abstract

Objectives] To study the anti-fatigue effect of water extract from Centella asiatica (L.) Urban on mice. [Methods] After intragastric administration of low, medium and high concentration of water extract from Centella asiatica (L.) Urban for 14 d, the rotarod time and the content of serum lactic acid in mice were determined, respectively. [Results] Compared with the control group, the rotarod time of mice in the low and medium concentration groups was significantly prolonged (P <0.05), but there was no significant difference between the control group and the high concentration group; the content of serum lactic acid in the medium concentration group was significantly lower than that in the control group (P<0.01), but there was no significant difference between low concentration group and high concentration group and the control group. [Conclusions] A certain concentration of water extract from Centella asiatica (L.) Urban had a good anti-fatigue effect.

Subjects

CENTELLA asiatica; MICE; LACTIC acid; CONTROL groups

Publication

Medicinal Plant, 2023, Vol 14, Issue 1, p49

ISSN

2152-3924

Publication type

Academic Journal

DOI

10.19600/j.cnki.issn2152-3924.2023.01.010