Anti-fungal effect of Horsetail hydroalcoholic extract against Candida albicans compared with nystatin: An in vitro study.

Amirinia, Fatemeh; Pourhajibagher, Maryam

Methods: In this experimental study, hydroalcoholic extract of Horsetail was prepared at concentrations of 4, 2, 1, 0.5, 0.25 and 0.12 mg/ml. C. albicans ATCC 10231 was cultured in Sabouraud Dextrose Agar (SDA) medium, and in each culture plate, one disk containing each concentration of plant extract, one 100-unit nystatin disc as positive control and one distilled water disks as negative control were placed. After 24 hours, the mean diameter of the inhibition zone of different concentrations of Horsetail extract and nystatin was compared by one-way ANOVA test. Result: The mean diameters of inhibition zone Horsetail extract at the concentrations of 4 and 2 mg/ml were 38 and 26 mm, respectively, whiles the diameter of inhibition zone of nystatin disc was 32 mm. The results showed that by increasing the concentration of Horsetail extract, the diameter of the inhibition zone increased. The inhibition zone diameter of the highest concentration of Horsetail extract was not significantly different with nystatin (p > 0.05) Conclusion: The results of this study showed that Horsetail extract could be considered as a suitable candidate for the elimination of oral infections caused by C. albicans.

IRAN; ANTIFUNGAL agents; CANDIDA albicans; CONFERENCES & conventions; MEDICINAL plants; NYSTATIN; PLANT extracts; PHARMACODYNAMICS

Current Medical Mycology, 2018, Vol 4, p188

2423-3439

Academic Journal

10.18502/cmm.4.S1.2018.180