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- Title
A mutation in RYK is a genetic factor for nonsyndromic cleft lip and palate.
- Authors
Watanabe, Akira; Akita, Sadanori; Tin, Nguyen Thi Duc; Natsume, Nagato; Nakano, Yoko; Niikawa, Norio; Uchiyama, Takeshi; Yoshiura, Koh-ichiro
- Abstract
The RYK, EPHB2, and EPHB3 genes are attractive candidates for cleft lip and/or palate and cleft palate only pathogenesis. Both the Ryk-deficient mouse and Ephb2/Ephb3 (genes for interaction molecules with RYK) double-mutant mouse show cleft palate.
- Publication
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2006, Vol 43, Issue 3, p310
- ISSN
1055-6656
- Publication type
Journal Article
- DOI
10.1597/04-145.1