We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effects of fluid and electrolyte management on amphotericin B-induced nephrotoxicity among extremely low birth weight infants.
- Authors
Holler, Bernd; Omar, Said A; Farid, Maged D; Patterson, Maria Jevitz
- Abstract
Greater use of invasive procedures and aggressive antimicrobial therapy predispose extremely low birth weight (ELBW) infants to systemic fungal sepsis. Despite its adverse effects (including renal and electrolyte disturbances), amphotericin B (amphoB) remains the preferred drug for fungal therapy. Multiple studies have indicated that sodium loading may prevent renal toxicity among animals and human adults. The effects of fluid and electrolyte management on amphoB-induced nephrotoxicity among ELBW infants have not been evaluated extensively. The purpose of this study was to examine the effects of fluid and electrolyte management on amphoB-induced nephrotoxicity among ELBW infants.
- Publication
Pediatrics, 2004, Vol 113, Issue 6, pe608
- ISSN
1098-4275
- Publication type
Journal Article
- DOI
10.1542/peds.113.6.e608