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- Title
A multicenter, randomized, controlled trial comparing Surfaxin (Lucinactant) lavage with standard care for treatment of meconium aspiration syndrome.
- Authors
Wiswell, Thomas E; Knight, Gail R; Finer, Neil N; Donn, Steven M; Desai, Hemant; Walsh, William F; Sekar, Krishnamurthy C; Bernstein, Graham; Keszler, Martin; Visser, Valya E; Merritt, T Allen; Mannino, Frank L; Mastrioianni, Lisa; Marcy, Brian; Revak, Susan D; Tsai, Huei; Cochrane, Charles G
- Abstract
Infants with meconium aspiration syndrome (MAS) have marked surfactant dysfunction. Airways and alveoli of affected neonates contain meconium, inflammatory cells, inflammatory mediators, edema fluid, protein, and other debris. The objective of this study was to compare treatment with bronchoalveolar lavage using dilute Surfaxin with standard therapy in a population of newborn infants with MAS.
- Publication
Pediatrics, 2002, Vol 109, Issue 6, p1081
- ISSN
1098-4275
- Publication type
Journal Article
- DOI
10.1542/peds.109.6.1081