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- Title
Role of L-carnitine in apnea of prematurity: a randomized, controlled trial.
- Authors
O'Donnell, Jane; Finer, Neil N; Rich, Wade; Barshop, Bruce A; Barrington, Keith J
- Abstract
Carnitine is thought to be a conditionally essential biological cofactor for premature infants. A preliminary study suggested that carnitine could significantly reduce apnea of prematurity. The objective of this study was to evaluate critically the role of carnitine in idiopathic apnea of prematurity and to determine whether the use of carnitine would facilitate discontinuation of mechanical ventilatory support, shorten the duration of ventilatory support, and reduce the amount of time that such infants are exposed to both mechanical ventilation and oxygen. We also wanted to determine the effects of supplemental carnitine on weight gain, time to regain birth weight, time to achieve full enteral feedings, and length of hospital stay.
- Publication
Pediatrics, 2002, Vol 109, Issue 4, p622
- ISSN
1098-4275
- Publication type
Journal Article
- DOI
10.1542/peds.109.4.622