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- Title
Hypotonic-hyporesponsive episodes reported to the Vaccine Adverse Event Reporting System (VAERS), 1996-1998.
- Authors
DuVernoy, T S; Braun, M M
- Abstract
A hypotonic-hyporesponsive episode (HHE) is the sudden onset of hypotonia, hyporesponsiveness, and pallor or cyanosis that occurs within 48 hours after childhood immunizations. This syndrome has been primarily associated with pertussis-containing vaccines administered to children <2 years of age, and has been estimated to occur once every 1750 diphtheria-tetanus-pertussis (DTwP) vaccinations. Previous studies of HHE were limited by small numbers of cases and, sometimes, by limited details of the event.
- Publication
Pediatrics, 2000, Vol 106, Issue 4, pE52
- ISSN
1098-4275
- Publication type
Journal Article
- DOI
10.1542/peds.106.4.e52