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- Title
Proarrhythmia associated with cisapride in children.
- Authors
Hill, S L; Evangelista, J K; Pizzi, A M; Mobassaleh, M; Fulton, D R; Berul, C I
- Abstract
Cisapride is a prokinetic agent that facilitates gastrointestinal motility and is widely used for the treatment of gastroesophageal reflux disease (GERD) in adults and children. However, reports of ventricular proarrhythmia have been noted in patients taking cisapride, particularly in conjunction with other drugs that may inhibit hepatic metabolism of cisapride via the cytochrome P450 3A4 system.
- Publication
Pediatrics, 1998, Vol 101, Issue 6, p1053
- ISSN
1098-4275
- Publication type
Journal Article
- DOI
10.1542/peds.101.6.1053