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- Title
Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.
- Authors
Wellinger, Raymund J; Zakian, Virginia A
- Abstract
The mechanisms that maintain the stability of chromosome ends have broad impact on genome integrity in all eukaryotes. Budding yeast is a premier organism for telomere studies. Many fundamental concepts of telomere and telomerase function were first established in yeast and then extended to other organisms. We present a comprehensive review of yeast telomere biology that covers capping, replication, recombination, and transcription. We think of it as yeast telomeres--soup to nuts.
- Publication
Genetics, 2012, Vol 191, Issue 4, p1073
- ISSN
1943-2631
- Publication type
Journal Article
- DOI
10.1534/genetics.111.137851