We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Cell polarization and cytokinesis in budding yeast.
- Authors
Bi, Erfei; Park, Hay-Oak
- Abstract
Asymmetric cell division, which includes cell polarization and cytokinesis, is essential for generating cell diversity during development. The budding yeast Saccharomyces cerevisiae reproduces by asymmetric cell division, and has thus served as an attractive model for unraveling the general principles of eukaryotic cell polarization and cytokinesis. Polarity development requires G-protein signaling, cytoskeletal polarization, and exocytosis, whereas cytokinesis requires concerted actions of a contractile actomyosin ring and targeted membrane deposition. In this chapter, we discuss the mechanics and spatial control of polarity development and cytokinesis, emphasizing the key concepts, mechanisms, and emerging questions in the field.
- Publication
Genetics, 2012, Vol 191, Issue 2, p347
- ISSN
1943-2631
- Publication type
Journal Article
- DOI
10.1534/genetics.111.132886