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- Title
Genome-wide epigenetic perturbation jump-starts patterns of heritable variation found in nature.
- Authors
Roux, Fabrice; Colomé-Tatché, Maria; Edelist, Cécile; Wardenaar, René; Guerche, Philippe; Hospital, Frédéric; Colot, Vincent; Jansen, Ritsert C; Johannes, Frank
- Abstract
We extensively phenotyped 6000 Arabidopsis plants with experimentally perturbed DNA methylomes as well as a diverse panel of natural accessions in a common garden. We found that alterations in DNA methylation not only caused heritable phenotypic diversity but also produced heritability patterns closely resembling those of the natural accessions. Our findings indicate that epigenetically induced and naturally occurring variation in complex traits share part of their polygenic architecture and may offer complementary adaptation routes in ecological settings.
- Publication
Genetics, 2011, Vol 188, Issue 4, p1015
- ISSN
1943-2631
- Publication type
Journal Article
- DOI
10.1534/genetics.111.128744