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- Title
A strategy for direct mapping and identification of mutations by whole-genome sequencing.
- Authors
Zuryn, Steven; Le Gras, Stéphanie; Jamet, Karine; Jarriault, Sophie
- Abstract
Mutant screens have proven powerful for genetic dissection of a myriad of biological processes, but subsequent identification and isolation of the causative mutations are usually complex and time consuming. We have made the process easier by establishing a novel strategy that employs whole-genome sequencing to simultaneously map and identify mutations without the need for any prior genetic mapping.
- Publication
Genetics, 2010, Vol 186, Issue 1, p427
- ISSN
1943-2631
- Publication type
Journal Article
- DOI
10.1534/genetics.110.119230