Works matching AU Breakefield, Xandra O.

Results: 125

Generation of stable retrovirus packaging cell lines after transduction with herpes simplex virus hybrid amplicon vectors.

Published in:

Journal of Gene Medicine, 2002, v. 4, n. 3, p. 229, doi. 10.1002/jgm.276

By:

Sena-Esteves, Miguel;
Hampl, Jürgen A.;
Camp, Sara M.;
Breakefield, Xandra O.

Publication type:

Article

Hybrid vector designs to control the delivery, fate and expression of transgenes.

Published in:

Journal of Gene Medicine, 2000, v. 2, n. 6, p. 395, doi. 10.1002/1521-2254(200011/12)2:6<395::AID-JGM146>3.0.CO;2-K

By:

Lam, Paula Y. P.;
Breakefield, Xandra O.

Publication type:

Article

Prodrug activation enzymes in cancer gene therapy.

Published in:

Journal of Gene Medicine, 2000, v. 2, n. 3, p. 148, doi. 10.1002/(SICI)1521-2254(200005/06)2:3<148::AID-JGM105>3.0.CO;2-Q

By:

Aghi, Manish;
Hochberg, Fred;
Breakefield, Xandra O.

Publication type:

Article

Combined HSV-1 recombinant and amplicon piggyback vectors: replication-competent and defective forms, and therapeutic efficacy for experimental gliomas.

Published in:

Journal of Gene Medicine, 1999, v. 1, n. 3, p. 176, doi. 10.1002/(SICI)1521-2254(199905/06)1:3<176::AID-JGM35>3.0.CO;2-T

By:

Pechan, Peter A.;
Herrlinger, Ulrich;
Aghi, Manish;
Jacobs, Andreas;
Breakefield, Xandra O.

Publication type:

Article

Biochemical and Cellular Analysis of Human Variants of the DYT1 Dystonia Protein, TorsinA/TOR1A.

Published in:

Human Mutation, 2014, v. 35, n. 9, p. 1101, doi. 10.1002/humu.22602

By:

Hettich, Jasmin;
Ryan, Scott D.;
Souza, Osmar Norberto;
Saraiva Macedo Timmers, Luís Fernando;
Tsai, Shelun;
Atai, Nadia A.;
Hora, Cintia C.;
Zhang, Xuan;
Kothary, Rashmi;
Snapp, Erik;
Ericsson, Maria;
Grundmann, Kathrin;
Breakefield, Xandra O.;
Nery, Flávia C.

Publication type:

Article

Exogenous loading of extracellular vesicles, virus-like particles, and lentiviral vectors with supercharged proteins.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03440-7

By:

Breyne, Koen;
Ughetto, Stefano;
Rufino-Ramos, David;
Mahjoum, Shadi;
Grandell, Emily A.;
de Almeida, Luís P.;
Breakefield, Xandra O.

Publication type:

Article

Secretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells.

Published in:

Cellular & Molecular Neurobiology, 2018, v. 38, n. 8, p. 1539, doi. 10.1007/s10571-018-0622-5

By:

Gustafsson, Gabriel;
Lööv, Camilla;
Persson, Emma;
Lázaro, Diana F.;
Takeda, Shuko;
Bergström, Joakim;
Erlandsson, Anna;
Sehlin, Dag;
Balaj, Leonora;
György, Bence;
Hallbeck, Martin;
Outeiro, Tiago F.;
Breakefield, Xandra O.;
Hyman, Bradley T.;
Ingelsson, Martin

Publication type:

Article

Brain Tumor Microvesicles: Insights into Intercellular Communication in the Nervous System.

Published in:

Cellular & Molecular Neurobiology, 2011, v. 31, n. 6, p. 949, doi. 10.1007/s10571-011-9697-y

By:

van der Vos, Kristan E.;
Balaj, Leonora;
Skog, Johan;
Breakefield, Xandra O.

Publication type:

Article

Gene Therapy for Brain Tumors.

Published in:

Brain Pathology, 1995, v. 5, n. 4, p. 345, doi. 10.1111/j.1750-3639.1995.tb00615.x

By:

Kramm, Christof M.;
Sena-Esteves, Miguel;
Barnett, Faith H.;
Rainov, Nikolai G.;
Schuback, Deborah E.;
Yu, John S.;
Pechan, Peter A.;
Paulus, Werner;
Chiocca, E. Antonio;
Breakefield, Xandra O.

Publication type:

Article

The Autosomal Dominant Dystonias.

Published in:

Brain Pathology, 1992, v. 2, n. 4, p. 297, doi. 10.1111/j.1750-3639.1992.tb00707.x

By:

Gasser, Thomas;
Fahn, Stanley;
Breakefield, Xandra O.

Publication type:

Article

Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy.

Published in:

Nature Medicine, 2012, v. 18, n. 12, p. 1835, doi. 10.1038/nm.2994

By:

Shao, Huilin;
Chung, Jaehoon;
Balaj, Leonora;
Charest, Alain;
Bigner, Darell D;
Carter, Bob S;
Hochberg, Fred H;
Breakefield, Xandra O;
Weissleder, Ralph;
Lee, Hakho

Publication type:

Article

Refocus the Recombinant DNA Advisory Committee.

Published in:

Nature Medicine, 2012, v. 18, n. 7, p. 1007, doi. 10.1038/nm0712-1007

By:

Breakefield, Xandra O

Publication type:

Article

Molecular Genetics of the Monoamine Oxidases.

Published in:

Journal of Neurochemistry, 1989, v. 53, n. 1, p. 12, doi. 10.1111/j.1471-4159.1989.tb07289.x

By:

Hsu, Yun-Pung P.;
Powell, John F.;
Sims, Katherine B.;
Breakefield, Xandra O.

Publication type:

Article

Structural Features of Human Monoamine Oxidase A Elucidated from cDNA and Peptide Sequences.

Published in:

Journal of Neurochemistry, 1988, v. 51, n. 4, p. 1321, doi. 10.1111/j.1471-4159.1988.tb03105.x

By:

Hsu, Yun-Pung P.;
Weyler, Walter;
Chen, Shiuan;
Sims, Katherine B.;
Rinehart, William B.;
Utterback, Margot C.;
Powell, John F.;
Breakefield, Xandra O.

Publication type:

Article

Targeting of Liposomes to Cells Bearing Nerve Growth Factor Receptors Mediated by Biotinylated Nerve Growth Factor.

Published in:

Journal of Neurochemistry, 1987, v. 48, n. 3, p. 865, doi. 10.1111/j.1471-4159.1987.tb05597.x

By:

Rosenberg, Michael B.;
Breakefield, Xandra O.;
Hawrot, Edward

Publication type:

Article

Receptor Binding Activities of Biotinylated Derivatives of β-Nerve Growth Factor.

Published in:

Journal of Neurochemistry, 1986, v. 46, n. 2, p. 641, doi. 10.1111/j.1471-4159.1986.tb13015.x

By:

Rosenberg, Michael B.;
Hawrot, Edward;
Breakefield, Xandra O.

Publication type:

Article

Soluble and Particulate Forms of Rat Catechol- O-Methyltransferase Distinguished by Gel Electrophoresis and Immune Fixation.

Published in:

Journal of Neurochemistry, 1985, v. 44, n. 2, p. 421, doi. 10.1111/j.1471-4159.1985.tb05432.x

By:

Grossman, Mark H.;
Creveling, C. R.;
Rybczynski, Robert;
Braverman, Muriel;
Isersky, Chaviva;
Breakefield, Xandra O.

Publication type:

Article

Differences in the Structure of A and B Forms of Human Monoamine Oxidase.

Published in:

Journal of Neurochemistry, 1981, v. 37, n. 2, p. 363, doi. 10.1111/j.1471-4159.1981.tb00464.x

By:

Cawthon, Richard M.;
Pintar, John E.;
Haseltine, Florence P.;
Breakefield, Xandra O.

Publication type:

Article

High-Affinity [3H]Choline Accumulation in Cultured Human Skin Fibroblasts.

Published in:

Journal of Neurochemistry, 1981, v. 36, n. 2, p. 746, doi. 10.1111/j.1471-4159.1981.tb01651.x

By:

Riker, Donald Kay;
Roth, Robert H.;
Breakefield, Xandra O.

Publication type:

Article

MONOAMINE OXIDASE ACTIVITY IN NORMAL and LESCH-NYHAN FIBROBLASTS.

Published in:

Journal of Neurochemistry, 1978, v. 31, n. 5, p. 1247, doi. 10.1111/j.1471-4159.1978.tb06249.x

By:

Edelstein, Susan B.;
Castiglione, Carmela M.;
Breakefield, Xandra O.

Publication type:

Article

THE CATECHOL ESTROGEN, 2-HYDROXYESTRADIOL, INHIBITS CATECHOL- O-METHYLTRANSFERASE ACTIVITY IN NEUROBLASTOMA CELLS.

Published in:

Journal of Neurochemistry, 1978, v. 31, n. 1, p. 245, doi. 10.1111/j.1471-4159.1978.tb12455.x

By:

Lloyd, Tom;
Weisz, Judith;
Breakefield, Xandra O.

Publication type:

Article

MONOAMINE OXIDASE A AND B IN CULTURED CELLS.

Published in:

Journal of Neurochemistry, 1978, v. 30, n. 6, p. 1391, doi. 10.1111/j.1471-4159.1978.tb10471.x

By:

Hawkins, Morris;
Breakefield, Xandra O.

Publication type:

Article

TRANSPORT OF TYROSINE, PHENYLALANINE, TRYPTOPHAN AND GLYCINE IN NEUROBLASTOMA CLONES.

Published in:

Journal of Neurochemistry, 1977, v. 28, n. 1, p. 127, doi. 10.1111/j.1471-4159.1977.tb07718.x

By:

Archer, Ellen G.;
Breakefield, Xandra O.;
Sharata, Mary N.

Publication type:

Article

RESERPINE SENSITIVITY OF CATECHOLAMINE METABOLISM IN MURINE NEUROBLASTOMA CLONE N1E-115.

Published in:

Journal of Neurochemistry, 1975, v. 25, n. 6, p. 877, doi. 10.1111/j.1471-4159.1975.tb04421.x

By:

Breakefield, Xandra O.

Publication type:

Article

[18F]-Dopa positron emission tomography imaging in early-stage, non-parkin juvenile parkinsonism.

Published in:

Movement Disorders, 2002, v. 17, n. 4, p. 789, doi. 10.1002/mds.10133

By:

Pal, Pramod K.;
Leung, Joanne;
Hedrich, Katya;
Samii, Ali;
Lieberman, Abraham;
Nausieda, Paul A.;
Calne, Donald B.;
Breakefield, Xandra O.;
Klein, Christine;
Stoessl, A. Jon

Publication type:

Article

Intrafamilial phenotypic variability of the DYT1 dystonia: From asymptomatic TOR1A gene carrier status to dystonic storm.

Published in:

Movement Disorders, 2002, v. 17, n. 2, p. 339, doi. 10.1002/mds.10096

By:

Opal, Puneet;
Tintner, Ron;
Jankovic, Joseph;
Leung, Joanne;
Breakefield, Xandra O.;
Friedman, Jennifer;
Ozelius, Laurie

Publication type:

Article

Phenotypic variability in a large kindred (Family LA) with deletions in the parkin gene.

Published in:

Movement Disorders, 2002, v. 17, n. 2, p. 424, doi. 10.1002/mds.10071

By:

Pramstaller, Peter P.;
Kis, Bernhard;
Eskelson, Cordula;
Hedrich, Katja;
Scherer, Monika;
Schwinger, Eberhard;
Breakefield, Xandra O.;
Kramer, Patricia L.;
Ozelius, Laurie J.;
Klein, Christine

Publication type:

Article

Untethering the Nuclear Envelope and Cytoskeleton: Biologically Distinct Dystonias Arising from a Common Cellular Dysfunction.

Published in:

International Journal of Cell Biology, 2012, p. 1, doi. 10.1155/2012/634214

By:

Atai, Nadia A.;
Ryan, Scott D.;
Kothary, Rashmi;
Breakefield, Xandra O.;
Nery, Flávia C.

Publication type:

Article

miR-21 in the Extracellular Vesicles (EVs) of Cerebrospinal Fluid (CSF): A Platform for Glioblastoma Biomarker Development.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0078115

By:

Akers, Johnny C.;
Ramakrishnan, Valya;
Kim, Ryan;
Skog, Johan;
Nakano, Ichiro;
Pingle, Sandeep;
Kalinina, Juliya;
Hua, Wei;
Kesari, Santosh;
Mao, Ying;
Breakefield, Xandra O.;
Hochberg, Fred H.;
Van Meir, Erwin G.;
Carter, Bob S.;
Chen, Clark C.

Publication type:

Article

Dopa-Responsive Dystonia: Functional Analysis of Single Nucleotide Substitutions within the 5’ Untranslated GCH1 Region.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076975

By:

Armata, Ioanna A.;
Balaj, Leonora;
Kuster, John K.;
Zhang, Xuan;
Tsai, Shelun;
Armatas, Andreas A.;
Multhaupt-Buell, Trisha J.;
Soberman, Roy;
Breakefield, Xandra O.;
Ichinose, Hiroshi;
Sharma, Nutan

Publication type:

Article

Stochastic Model of Tsc1 Lesions in Mouse Brain

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064224

By:

Prabhakar, Shilpa;
Goto, June;
Zuang, Xuan;
Sena-Esteves, Miguel;
Bronson, Roderick;
Brockmann, Jillian;
Gianni, Davide;
Wojtkiewicz, Gregory R.;
Chen, John W.;
Stemmer-Rachamimov, Anat;
Kwiatkowski, David J.;
Breakefield, Xandra O.

Publication type:

Article

dtorsin, the Drosophila Ortholog of the Early-Onset Dystonia TOR1A (DYT1), Plays a Novel Role in Dopamine Metabolism.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026183

By:

Wakabayashi-Ito, Noriko;
Doherty, Olugbenga M.;
Moriyama, Hideaki;
Breakefield, Xandra O.;
Gusella, James F.;
O'Donnell, Janis M.;
Ito, Naoto

Publication type:

Article

Down-Regulation of miR-101 in Endothelial Cells Promotes Blood Vessel Formation through Reduced Repression of EZH2.

Published in:

PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016282

By:

Smits, Michiel;
Mir, Shahryar E.;
Nilsson, R. Jonas A.;
van der Stoop, Petra M.;
Niers, Johanna M.;
Marquez, Victor E.;
Cloos, Jacqueline;
Breakefield, Xandra O.;
Krichevsky, Anna M.;
Noske, David P.;
Tannous, Bakhos A.;
Würdinger, Thomas

Publication type:

Article

Impaired Motor Learning in Mice Expressing TorsinA with the DYT1 Dystonia Mutation.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 22, p. 5351, doi. 10.1523/JNEUROSCI.0855-05.2005

By:

Sharma, Nutan;
Baxter, Mark G.;
Petravicz, Jeremy;
Bragg, D. Cristopher;
Schienda, Alonna;
Standaert, David G.;
Breakefield, Xandra O.

Publication type:

Article

Dystonia gene in Ashkenazi Jewish population is located on chromosome 9q32-34.

Published in:

Annals of Neurology, 1990, v. 27, n. 2, p. 114, doi. 10.1002/ana.410270203

By:

Kramer, Patricia L.;
De Leon, Deborah;
Ozelius, Laurie;
Risch, Neil;
Bressman, Susan B.;
Brin, Mitchell F.;
Schuback, Deborah E.;
Burke, Robert E.;
Kwiatkowski, David J.;
Shale, Heidi;
Gusella, James F.;
Breakefield, Xandra O.;
Fahn, Stanley

Publication type:

Article

Glial growth factor-like activity in Schwann cell tumors.

Published in:

Annals of Neurology, 1986, v. 20, n. 3, p. 317, doi. 10.1002/ana.410200308

By:

Brockes, Jeremy P.;
Breakefield, Xandra O.;
Martuza, Robert L.

Publication type:

Article

Phenylalanine hydroxylase in melanoma cells.

Published in:

Journal of Cellular Physiology, 1978, v. 94, n. 3, p. 307, doi. 10.1002/jcp.1040940308

By:

Breakefield, Xandra O.;
Castiglione, Carmela M.;
Halaban, Ruth;
Pawelek, John;
Shiman, Ross

Publication type:

Article

Longitudinal analysis of serum-derived extracellular vesicle RNA to monitor dacomitinib treatment response in EGFR-amplified recurrent glioblastoma patients.

Published in:

Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad104

By:

Yekula, Anudeep;
Hsia, Tiffaney;
Kitchen, Robert R;
Chakrabortty, Sudipto K;
Yu, Wei;
Batool, Syeda M;
Lewis, Brian;
Szeglowski, Antoni J;
Weissleder, Ralph;
Lee, Hakho;
Chi, Andrew S;
Batchelor, Tracy;
Carter, Bob S;
Breakefield, Xandra O;
Skog, Johan;
Balaj, Leonora

Publication type:

Article

Update from the 2013 international neurofibromatosis conference.

Published in:

American Journal of Medical Genetics. Part A, 2014, v. 164A, n. 12, p. 2969, doi. 10.1002/ajmg.a.36754

By:

Plotkin, Scott R.;
Albers, Anne C.;
Babovic ‐ Vuksanovic, Dusica;
Blakeley, Jaishri O.;
Breakefield, Xandra O.;
Dunn, Courtney M.;
Evans, D. Gareth;
Fisher, Michael J.;
Friedman, Jan M.;
Giovannini, Marco;
Gutmann, David H.;
Kalamarides, Michel;
McClatchey, Andrea I.;
MessiaEN, Ludwine;
Morrison, HelEN;
Parkinson, David B.;
Stemmer ‐ Rachamimov, Anat O.;
Van Raamsdonk, Catherine D.;
Riccardi, VincENt M.;
Rosser, TENa

Publication type:

Article

TorsinA in PC12 cells: Localization in the endoplasmic reticulum and response to stress.

Published in:

Journal of Neuroscience Research, 2003, v. 72, n. 2, p. 158, doi. 10.1002/jnr.10567

By:

Jeffrey Hewett;
Philipp Ziefer;
Daniele Bergeron;
Teri Naismith;
Heather Boston;
Damien Slater;
Jeremy Wilbur;
Deborah Schuback;
Christoph Kamm;
Nicole Smith;
Sara Camp;
Laurie J. Ozelius;
Vijaya Ramesh;
Phyllis I. Hanson;
Xandra O. Breakefield

Publication type:

Article

Emerging Roles of Extracellular Vesicles in the Nervous System.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 46, p. 15482, doi. 10.1523/JNEUROSCI.3258-14.2014

By:

Rajendran, Lawrence;
Bali, Jitin;
Barr, Maureen M.;
Court, Felipe A.;
Krämer-Albers, Eva-Maria;
Picou, Frederic;
Raposo, Graça;
van der Vos, Kristan E.;
van Niel, Guillaume;
Juan Wang;
Breakefield, Xandra O.

Publication type:

Article

Extracellular vesicles: biology and emerging therapeutic opportunities.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 5, p. 347, doi. 10.1038/nrd3978

By:

EL Andaloussi, Samir;
Mäger, Imre;
Breakefield, Xandra O.;
Wood, Matthew J. A.

Publication type:

Article

Heparin affinity purification of extracellular vesicles.

Published in:

Scientific Reports, 2015, p. 10266, doi. 10.1038/srep10266

By:

Balaj, Leonora;
Atai, Nadia A.;
Chen, Weilin;
Mu, Dakai;
Tannous, Bakhos A.;
Breakefield, Xandra O.;
Skog, Johan;
Maguire, Casey A.

Publication type:

Article

Roles of extracellular vesicles in glioblastoma: foes, friends and informers.

Published in:

Frontiers in Oncology, 2023, p. 1

By:

Lunavat, Taral R.;
Nieland, Lisa;
Vrijmoet, Anne B.;
Zargani-Piccardi, Ayrton;
Samaha, Youssef;
Breyne, Koen;
Breakefield, Xandra O.

Publication type:

Article

De novo mutations (GAG deletion) in the DYT1 gene in two non-Jewish patients with early-onset dystonia.

Published in:

Human Molecular Genetics, 1998, v. 7, n. 7, p. 1133, doi. 10.1093/hmg/7.7.1133

By:

Klein, Christine;
Brin, Mitchell F.;
de Leon, Deborah;
Limborska, Svetlana A.;
Ivanova‐Smolenskaya, Irina A.;
Bressman, Susan B.;
Friedman, Andrzej;
Markova, Elena D.;
Risch, Neil J.;
Breakefield, Xandra O.;
Ozelius, Laurie J.

Publication type:

Article

Analysis of extracellular mRNA in human urine reveals splice variant biomarkers of muscular dystrophies.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06206-0

By:

Antoury, Layal;
Hu, Ningyan;
Balaj, Leonora;
Das, Sudeshna;
Georghiou, Sofia;
Darras, Basil;
Clark, Tim;
Breakefield, Xandra O.;
Wheeler, Thurman M.

Publication type:

Article

Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02261-1

By:

Reátegui, Eduardo;
van der Vos, Kristan E.;
Lai, Charles P.;
Zeinali, Mahnaz;
Atai, Nadia A.;
Aldikacti, Berent;
Floyd Jr., Frederick P.;
Khankhel, Aimal H.;
Thapar, Vishal;
Hochberg, Fred H.;
Sequist, Lecia V.;
Nahed, Brian V.;
Carter, Bob S.;
Toner, Mehmet;
Balaj, Leonora;
Ting, David T.;
Breakefield, Xandra O.;
Stott, Shannon L.

Publication type:

Article

Cathechol-O-methyltransferase activity in cultured human skin fibroblasts from controls and patients with dystonia musculorum deformans.

Published in:

Journal of Neuroscience Research, 1981, v. 6, n. 3, p. 349, doi. 10.1002/jnr.490060310

By:

Breakefield, Xandra O.;
Braverman, Muriel;
Riker, Donald Kay;
Giller, Earl L.

Publication type:

Article

ε-sarcoglycan mutations found in combination with other dystonia gene mutations.

Published in:

Annals of Neurology, 2002, v. 52, n. 5, p. 675, doi. 10.1002/ana.10358

By:

Klein, Christine;
Liu, Liu;
Doheny, Dana;
Kock, Norman;
Müller, Birgitt;
De Carvalho Aguiar, Patricia;
Leung, Joanne;
De Leon, Deborah;
Bressman, Susan B.;
Silverman, Jeremy;
Smith, Christopher;
Danisi, Fabio;
Morrison, Chris;
Walker, Ruth H.;
Velickovic, Miodrag;
Schwinger, Eberhard;
Kramer, Patricia L.;
Breakefield, Xandra O.;
Brin, Mitchell F.;
Ozelius, Laurie J.

Publication type:

Article

Role of parkin mutations in 111 community-based patients with early-onset parkinsonism.

Published in:

2002

By:

Kann, Martin;
Jacobs, Helfried;
Mohrmann, Kathrin;
Schumacher, Kirsten;
Hedrich, Katja;
Garrels, Jennifer;
Wiegers, Karin;
Schwinger, Eberhard;
Pramstaller, Peter P.;
Breakefield, Xandra O.;
Ozelius, Laurie J.;
Vieregge, Peter;
Klein, Christine

Publication type:

journal article