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- Title
Isolated IgE reactivity to native walnut vicilin-like protein (nJug r 2) on ISAC™ microarray is due to cross-reactive carbohydrate epitopes.
- Authors
Villalta, Danilo; Conte, Mariaelisabetta; Asero, Riccardo; Da Re, Mirella; Stella, Sergio; Martelli, Paola
- Abstract
The last version of the microarray-based testing ImmunoCAP ISAC 112™ includes the native walnut (Junglans regia) molecules 2S albumin (nJug r 1), vicilin (nJug r 2) and lipid transfer protein (nJug r 3). In view of the many unexpected cases of isolated positivity to nJug r 2 occurring in daily practice, we evaluated the association of these reactivities with clinical symptoms, as well as the relationship between sIgE and nJug r 2 and cross-reactive carbohydrate determinants (CCDs).
- Publication
Clinical chemistry and laboratory medicine, 2013, Vol 51, Issue 10, p1991
- ISSN
1437-4331
- Publication type
Journal Article
- DOI
10.1515/cclm-2013-0027