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- Title
Increased circulating advanced glycation endproducts (AGEs) in acute trauma patients.
- Authors
Schulman, Carl I; Uribarri, Jaime; Cai, Weijing; Manning, Ron; Landy, David C; Gallardo, Margaret; Castillo, Angela; Namias, Nicholas; Striker, Gary E; Livingstone, Alan; Vlassara, Helen
- Abstract
Circulating levels of pro-inflammatory advanced glycation end products (AGEs) are increased in diabetes and other conditions characterized by chronically elevated oxidant stress (OS). OS also increases after acute trauma and is implicated in the development of complications such as multiple organ failure. Herein, we assess the effect of acute OS on circulating levels of AGEs in a cohort of acute trauma victims.
- Publication
Clinical chemistry and laboratory medicine, 2014, Vol 52, Issue 1, p103
- ISSN
1437-4331
- Publication type
Journal Article
- DOI
10.1515/cclm-2012-0834