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- Title
Splicing of a rare class of introns by the U12-dependent spliceosome.
- Authors
Will, Cindy L; Lührmann, Reinhard
- Abstract
Pre-mRNA splicing is catalyzed by two unique spliceosomes, designated U2- or U12-dependent. In contrast to the well-characterized U2-dependent spliceosome, much remains to be learned about the less abundant U12-type spliceosome. This review focuses on recent advances in elucidating the structure and function of the minor U12-dependent spliceosome. Interesting similarities and differences between the U12- and U2-dependent spliceosomes are also highlighted.
- Publication
Biological chemistry, 2005, Vol 386, Issue 8, p713
- ISSN
1431-6730
- Publication type
Journal Article
- DOI
10.1515/BC.2005.084