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- Title
Liver enzyme alteration: a guide for clinicians.
- Authors
Giannini, Edoardo G; Testa, Roberto; Savarino, Vincenzo
- Abstract
Isolated alterations of biochemical markers of liver damage in a seemingly healthy patient can present a challenge for the clinician. In this review we provide a guide to interpreting alterations to liver enzyme levels. The functional anatomy of the liver and pathophysiology of liver enzyme alteration are briefly reviewed. Using a schematic approach that classifies enzyme alterations as predominantly hepatocellular or predominantly cholestatic, we review abnormal enzymatic activity within the 2 subgroups, the most common causes of enzyme alteration and suggested initial investigations.
- Publication
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2005, Vol 172, Issue 3, p367
- ISSN
1488-2329
- Publication type
Journal Article
- DOI
10.1503/cmaj.1040752