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- Title
APOE genotype effects on Alzheimer's disease onset and epidemiology.
- Authors
Ashford, J Wesson
- Abstract
The risk of developing Alzheimer's disease (AD) is tied most closely to age and appears to follow Gompertzian kinetics. However, specific genetic factors are also linked closely to AD, and the apolipoprotein E (APOE) genotype accounts for as much of 50% of the attributable risk for AD in many populations. This paper reviews the onset, diagnosis, and epidemiology of AD, specifically with regard to the APOE genotype and the interaction of the genotype with age.
- Publication
Journal of molecular neuroscience : MN, 2004, Vol 23, Issue 3, p157
- ISSN
0895-8696
- Publication type
Journal Article
- DOI
10.1385/JMN:23:3:157