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- Title
Processed B-type natriuretic peptide is a biomarker of postinterventional restenosis in ischemic heart disease.
- Authors
Fujimoto, Hirotaka; Suzuki, Toru; Aizawa, Kenichi; Sawaki, Daigo; Ishida, Junichi; Ando, Jiro; Fujita, Hideo; Komuro, Issei; Nagai, Ryozo
- Abstract
Restenosis, a condition in which the lesion vessel renarrows after a coronary intervention procedure, remains a limitation in management. A surrogate biomarker for risk stratification of restenosis would be welcome. B-type natriuretic peptide (BNP) is secreted in response to pathologic stress from the heart. Its use as a biomarker of heart failure is well known; however, its diagnostic potential in ischemic heart disease is less explored. Recently, it has been reported that processed forms of BNP exist in the circulation. We hypothesized that circulating processed forms of BNP might be a biomarker of ischemic heart disease.
- Publication
Clinical chemistry, 2013, Vol 59, Issue 9, p1330
- ISSN
1530-8561
- Publication type
Journal Article
- DOI
10.1373/clinchem.2013.203406