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- Title
Full-length characterization of proteins in human populations.
- Authors
Borges, Chad R; Rehder, Doug S; Jarvis, Jason W; Schaab, Mathew R; Oran, Paul E; Nelson, Randall W
- Abstract
Diversity in human proteins often gives rise to pluralities of structurally similar but functionally distinct proteins. Such microheterogeneity generally escapes proteomics discovery technologies, as well as conventional immunometric assays. As an intermediate between these 2 technological approaches, targeted, full-length characterization of proteins using mass spectrometry is a suitable means of defining microheterogeneity evident in human populations.
- Publication
Clinical chemistry, 2010, Vol 56, Issue 2, p202
- ISSN
1530-8561
- Publication type
Journal Article
- DOI
10.1373/clinchem.2009.134858