Title

Ploidy changes in human fungal pathogens: Going beyond sexual reproduction.

Authors

Du, Han; Zheng, Qiushi; Bennett, Richard J.; Huang, Guanghua

Abstract

For example, cells of increasing ploidy often exhibit an increase in size that results in a smaller cell surface-to-volume ratio that may alter cell properties. I neoformans i cells are able to switch between haploid and diploid states through a sexual cycle, where the diploid state immediately undergoes meiosis and ploidy reduction. Asexual ploidy shifts, which describe changes in complete sets of chromosomes via a nonsexual reproductive cycle, are widespread in nature.

Subjects

PLOIDY; MEIOSIS; POLYPLOIDY; SEXUAL cycle; ANTIFUNGAL agents

Publication

PLoS Pathogens, 2022, Vol 18, Issue 12, p1

ISSN

1553-7366

Publication type

Academic Journal

DOI

10.1371/journal.ppat.1010954