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- Title
Fractional anisotropy in corpus callosum is associated with facilitation of motor representation during ipsilateral hand movements.
- Authors
Chiou, Shin-Yi; Wang, Ray-Yau; Roberts, R Edward; Wu, Yu-Te; Lu, Chia-Feng; Liao, Kwong-Kum; Yang, Yea-Ru
- Abstract
Coactivation of primary motor cortex ipsilateral to a unilateral movement (M1(ipsilateral)) has been observed, and the magnitude of activation is influenced by the contracting muscles. It has been suggested that the microstructural integrity of the callosal motor fibers (CMFs) connecting M1 regions may reflect the observed response. However, the association between the structural connectivity of CMFs and functional changes in M1(ipsilateral) remains unclear. The purpose of this study was to investigate the relationship between functional changes within M1(ipsilateral) during unilateral arm or leg movements and the microstructure of the CMFs connecting both homotopic representations (arm or leg).
- Publication
PloS one, 2014, Vol 9, Issue 8, pe104218
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0104218