We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Tendon repair is compromised in a high fat diet-induced mouse model of obesity and type 2 diabetes.
- Authors
David, Michael A; Jones, Khyrie H; Inzana, Jason A; Zuscik, Michael J; Awad, Hani A; Mooney, Robert A
- Abstract
The obesity epidemic has resulted in a large increase in type 2 diabetes (T2D). While some secondary complications of T2D are well recognized and their cellular and molecular mechanisms are defined, the impact of T2D on the musculoskeletal system is less understood. Clinical evidence suggests that tendon strength and repair are compromised. Here, a mouse model of obesity and T2D recapitulates the deleterious effects of this condition on tendon repair.
- Publication
PloS one, 2014, Vol 9, Issue 3, pe91234
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0091234