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- Title
Effect and mechanism of thrombospondin-1 on the angiogenesis potential in human endothelial progenitor cells: an in vitro study.
- Authors
Qin, Qing; Qian, Juying; Ge, Lei; Shen, Li; Jia, Jianguo; Jin, Jianhao; Ge, Junbo
- Abstract
Coronary collateral circulation plays a protective role in patients with coronary artery disease (CAD). We investigated whether thrombospondin-1(TSP-1) has an inhibitory effect on angiogenesis potential in endothelial progenitor cells(EPCs) and tested whether TSP-1 are altered in plasma of patients who had chronic total occlusion (CTO) in at least one coronary artery and with different collateral stages(according to Rentrop grading system).
- Publication
PloS one, 2014, Vol 9, Issue 2, pe88213
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0088213