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- Title
The degree of segmental aneuploidy measured by total copy number abnormalities predicts survival and recurrence in superficial gastroesophageal adenocarcinoma.
- Authors
Davison, Jon M; Yee, Melissa; Krill-Burger, J Michael; Lyons-Weiler, Maureen A; Kelly, Lori A; Sciulli, Christin M; Nason, Katie S; Luketich, James D; Michalopoulos, George K; LaFramboise, William A
- Abstract
Prognostic biomarkers are needed for superficial gastroesophageal adenocarcinoma (EAC) to predict clinical outcomes and select therapy. Although recurrent mutations have been characterized in EAC, little is known about their clinical and prognostic significance. Aneuploidy is predictive of clinical outcome in many malignancies but has not been evaluated in superficial EAC.
- Publication
PloS one, 2014, Vol 9, Issue 1, pe79079
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0079079