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- Title
DNA repair gene XRCC1 polymorphisms and head and neck cancer risk: an updated meta-analysis including 16344 subjects.
- Authors
Lou, Yin; Peng, Wen-jia; Cao, Dong-sheng; Xie, Juan; Li, Hong-hong; Jiang, Zheng-xuan
- Abstract
DNA repair gene X-ray repair cross complementing group 1 (XRCC1) plays an important role in the maintenance of the genomic integrity and protection of cells from DNA damage. Sequence variation in XRCC1 gene may alter head and neck cancer (HNC) susceptibility. However, these results are inconclusive. To derive a more precise estimation of the relationship between XRCC1 polymorphism and HNC risk, we undertook a meta-analysis involving 16,344 subjects.
- Publication
PloS one, 2013, Vol 8, Issue 9, pe74059
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0074059