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- Title
Effect of propofol in the immature rat brain on short- and long-term neurodevelopmental outcome.
- Authors
Karen, Tanja; Schlager, Gerald W; Bendix, Ivo; Sifringer, Marco; Herrmann, Ralf; Pantazis, Christos; Enot, David; Keller, Matthias; Kerner, Thoralf; Felderhoff-Mueser, Ursula
- Abstract
Propofol is commonly used as sedative in newborns and children. Recent experimental studies led to contradictory results, revealing neurodegenerative or neuroprotective properties of propofol on the developing brain. We investigated neurodevelopmental short- and long-term effects of neonatal propofol treatment.
- Publication
PloS one, 2013, Vol 8, Issue 5, pe64480
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0064480