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Title
Induced sputum MMP-1, -3 & -8 concentrations during treatment of tuberculosis.
Authors
Ugarte-Gil, Cesar A; Elkington, Paul; Gilman, Robert H; Coronel, Jorge; Tezera, Liku B; Bernabe-Ortiz, Antonio; Gotuzzo, Eduardo; Friedland, Jon S; Moore, David A J
Abstract
Tuberculosis (TB) destroys lung tissues and this immunopathology is mediated in part by Matrix Metalloproteinases (MMPs). There are no data on the relationship between local tissue MMPs concentrations, anti-tuberculosis therapy and sputum conversion.