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- Title
Feasibility of azacitidine added to standard chemotherapy in older patients with acute myeloid leukemia--a randomised SAL pilot study.
- Authors
Krug, Utz; Koschmieder, Anja; Schwammbach, Daniela; Gerss, Joachim; Tidow, Nicola; Steffen, Björn; Bug, Gesine; Brandts, Christian H; Schaich, Markus; Röllig, Christoph; Thiede, Christian; Noppeney, Richard; Stelljes, Matthias; Büchner, Thomas; Koschmieder, Steffen; Dührsen, Ulrich; Serve, Hubert; Ehninger, Gerhard; Berdel, Wolfgang E; Müller-Tidow, Carsten
- Abstract
Older patients with acute myeloid leukemia (AML) experience short survival despite intensive chemotherapy. Azacitidine has promising activity in patients with low proliferating AML. The aim of this dose-finding part of this trial was to evaluate feasibility and safety of azacitidine combined with a cytarabine- and daunorubicin-based chemotherapy in older patients with AML.
- Publication
PloS one, 2012, Vol 7, Issue 12, pe52695
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0052695