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- Title
Temperature variations around medication cassette and carry bag in routine use of epoprostenol administration in healthy volunteers.
- Authors
Tamura, Yuichi; Nakajima, Yasuo; Ozeki, Yasushi; Ono, Tomohiko; Takei, Makoto; Yamamoto, Tsunehisa; Fukuda, Keiichi
- Abstract
According to several treatment guidelines, epoprostenol is an important treatment option for pulmonary arterial hypertension. However, the pharmacokinetic characteristics and poor stability of epoprostenol at room temperature make its administration challenging. We therefore studied temperature fluctuations between the drug administration cassette and atmosphere to promote the safe use of epoprostenol.
- Publication
PloS one, 2012, Vol 7, Issue 12, pe52216
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0052216