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- Title
Development of implant/interconnected porous hydroxyapatite complex as new concept graft material.
- Authors
Doi, Kazuya; Oue, Hiroshi; Morita, Koji; Kajihara, Shiho; Kubo, Takayasu; Koretake, Katsunori; Perrotti, Vittoria; Iezzi, Giovanna; Piattelli, Adriano; Akagawa, Yasumasa
- Abstract
Dental implant has been successfully used to replace missing teeth. However, in some clinical situations, implant placement may be difficult because of a large bone defect. We designed novel complex biomaterial to simultaneously restore bone and place implant. This complex was incorporated implant into interconnected porous calcium hydroxyapatite (IP-CHA). We then tested this Implant/IP-CHA complex and evaluated its effect on subsequent bone regeneration and implant stability in vivo.
- Publication
PloS one, 2012, Vol 7, Issue 11, pe49051
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0049051