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- Title
Use of a single hybrid imaging agent for integration of target validation with in vivo and ex vivo imaging of mouse tumor lesions resembling human DCIS.
- Authors
Buckle, Tessa; Kuil, Joeri; van den Berg, Nynke S; Bunschoten, Anton; Lamb, Hildo J; Yuan, Hushan; Josephson, Lee; Jonkers, Jos; Borowsky, Alexander D; van Leeuwen, Fijs W B
- Abstract
Screening of biomarker expression levels in tumor biopsy samples not only provides an assessment of prognostic and predictive factors, but may also be used for selection of biomarker-specific imaging strategies. To assess the feasibility of using a biopsy specimen for a personalized selection of an imaging agent, the chemokine receptor 4 (CXCR4) was used as a reference biomarker.
- Publication
PloS one, 2013, Vol 8, Issue 1, pe48324
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0048324